Biography
Dr. Lai is also a clinical investigator with a robust research program dedicated to improving the lives of patients living with chronic liver disease and to help more of them survive to transplant and thrive after. Her research program has been continuously supported by numerous organizations including the National Institutes of Health, American Association for the Study of Liver Diseases (AASLD), American Gastroenterological Association (AGA), American College of Gastroenterology (ACG), American Society of Transplantation (AST), and American Federation for Aging Research (AFAR), in addition to the generous support of grateful patients. She serves as director of the UCSF Health Advancing Research in Clinical Hepatology (ARCH), the research arm of the UCSF Division of GI/Hepatology, as well as director of Patient-Facing Research Core of the NIH-funded UCSF Liver Center.
Dr. Lai earned her B.S. from Stanford University and combined MD/MBA degrees from Tufts University School of Medicine, then completed her clinical training in Internal Medicine at Columbia University, and gastroenterology and advanced/transplant hepatology fellowships at UCSF. Dr. Lai has received many honors for her work including the SF Business Times Top 40 under 40 Leader award, AGA Young Investigator Award in Clinical Science, AST Clinical Science Career Development Award, Young Investigator Award from the International Liver Transplantation Society, and the UCSF Department of Medicine Resident Research Award. Currently, Dr. Lai serves as an Associate Editor for the Hepatology Journal (the premier hepatology journal) and a standing member of the U.S. FDA Gastrointestinal Drug Advisory Committee.
If you are interested in contributing to Dr. Lai's research program, please consider making a tax-deductible contribution: https://makeagift.ucsf.edu/LaiResearchFund
Awards & Honors
Award | Conferred By | Date |
---|---|---|
Distinction in Mentoring (UCSF Academic Senate) | UCSF | 2023 |
Long-Term Mentor Award | UCSF Medical School | 2021 |
Young Investigator Award in Clinical Science | American Gastroenterological Association (AGA) | 2020 |
Floyd Rector Internal Medicine Research Mentoring Award | UCSF | 2019 |
Fellow | American Society of Transplantation | 2017 |
AST/Novartis Faculty Development Award (grant) | American Society of Transplantation | 2016 |
Clinical Science Career Development Award | American Society of Transplantation | 2016 |
New Investigator Award | American Geriatrics Society | 2015 |
Young Investigator Award | International Liver Transplantation Society | 2015 |
Top 40 under 40 | San Francisco Business Times | 2015 |
Paul B. Beeson Scholar in Aging Research (grant) | American Federation for Aging Research | 2014 |
Associate Scholar Genius Award (grant) | UCSF Pepper Center | 2014 |
T. Franklin Williams Scholar (grant) | Association of Specialty Professors | 2013 |
Junior Faculty Career Development Award (grant) | American College of Gastroenterology | 2012 |
Transplant Hepatology Fellowship (grant) | American Association for the Study of Liver Diseases | 2011 |
Clinical Research Award (grant) | American College of Gastrenterology | 2011 |
Vanguard Award | International Liver Transplantation Society | 2011 |
Sylvia Allison Kaplan Clinical Research Award | Northern California Kaiser Permanente | 2009 |
Alpha Omega Alpha | Tufts University School of Medicine | 2005 |
Education
Institution | Degree | Dept or School | End Date |
---|---|---|---|
UCSF | Diversity, Equity, and Inclusion Champion | 2021 | |
Columbia University Medical Center | Internship/Residency | Internal Medicine | |
Stanford University | B.S. | ||
Tufts University School of Medicine | M.D./M.B.A. | Medicine / Healthcare administration | |
UCSF | Advanced Training in Clinical Research | ||
UCSF | Fellowship in Advanced/Transplant Hepatology | ||
UCSF | Fellowship in Gastroenterology | ||
University of Louisville | Physician nutrition fellowship |
Board Certifications
American Board of Internal Medicine
American Board of Internal Medicine - Gastroenterology
Collaboration Interests
I am interested in:
- physician scientist
Clinical Expertise
Alcoholic Liver Disease
Autoimmune Hepatitis
Cirrhosis
Drug-Induced Hepatitis
Fulminant Hepatic Failure
Hemochromatosis
Hepatitis B
Hepatitis C
Hepatocellular Carcinoma (Liver Cancer)
Liver Transplantation
Living Donor Liver Transplantation
Nonalcoholic Fatty Liver Disease
Polycystic Liver Disease
Primary Biliary Cirrhosis
Primary Sclerosing Cholangitis
Clinical Trials
- Functional Assessment in Liver Transplantation (NCT03228290)Related Conditions: Liver Disease, Liver Transplant| Start Date: | End Date:
- ALTA TIPS: A 5-year Longitudinal Observational Study of Patients Undergoing TIPS Placement (NCT03973372)Related Conditions: Cirrhosis, High Blood Pressure| Start Date: | End Date:
- Exercise Intervention in Liver Transplant Patients (NCT02367092)Related Conditions: Liver Disease, Sarcopenia, Liver Cirrhoses, Liver Transplant, Cirrhosis| Start Date: | End Date:
Program Affiliations
UCSF Liver Center
In the News
Grants and Funding
- The spectrum of cognitive impairment including Alzheimer’s Disease and related dementias after liver transplantation | NIH/NIA | 2023-09-15 - 2028-08-31 | Role: PI
- Investigating the role of frailty on outcomes in acutely ill patients with cirrhosis undergoing liver transplantation in the acute care setting | NIH/NIDDK | 2023-07-15 - 2028-06-30 | Role: PI
- The Impact of Frailty on Liver Transplant Outcomes in Older Adults with Hepatocellular Carcinoma | NIH/NIA | 2023-01-15 - 2027-12-31 | Role: PI
- Predicting post-transplant mortality and global functional health based on pre-transplant functional status in liver transplantation | NIH | 2018-06-15 - 2023-05-31 | Role: PI
- UCSF Liver Center | NIH | 1985-07-01 - 2023-05-31 | Role: Co-Investigator
- Development of a laboratory frailty index to improve prediction of mortality in patients with cirrhosis awaiting liver transplantation | NIH | 2020-05-01 - 2022-04-30 | Role: Principal Investigator
- Frailty and Functional Status in Older Liver Transplant Patients | NIH | 2014-09-15 - 2019-08-31 | Role: Principal Investigator
- Global Functional Status in the Older Liver Transplant Candidate | NIH | 2013-08-15 - 2015-07-31 | Role: Principal Investigator
Research Narrative
Dr. Lai has engaged in research investigating clinical outcomes in patients with chronic liver disease. Her research focuses on three main areas:
1) Understanding the impact of functional status and physiologic reserve (i.e., frailty) in patients with cirrhosis awaiting liver transplantation (actively enrolling)
2) Evaluating the association between chronic hepatitis C and systemic inflammation with Vitamin D status and bone mineral density (actively enrolling)
3) Characterizing patterns of liver allocation and distribution and their association with liver transplant outcomes (both pre- and post-transplant) on a national level
Research Interests
Impact of function status in patients on the liver-transplant waiting list
Hepatitis C virus (HCV)
Patterns of donor liver allocation and liver transplant outcomes
Publications
- Psychological Distress is Prevalent and Interdependent Among Patients with Decompensated Cirrhosis and Their Caregivers.| | PubMed
- A patient-centered approach to dietary supplements for patients with chronic liver disease.| | PubMed
- Evaluating the positive predictive value of code-based identification of cirrhosis and its complications utilizing GPT-4.| | PubMed
- Predictors of long-term clinical outcomes after TIPS: An ALTA group study.| | PubMed
- Investigating the Association between Steatotic Liver Disease and CKD in a Nationally Representative Sample.| | PubMed
- Challenges in Liver Transplantation for Hepatocellular Carcinoma: A Review of Current Controversies.| | PubMed
- Decreasing Case Fatality Rates for Patients With Cirrhosis Infected With SARS-CoV-2: A National COVID Cohort Collaborative Study.| | PubMed
- Cystatin C and the difference between cystatin C and serum creatinine: Improved metrics to predict waitlist mortality among patients with decompensated cirrhosis.| | PubMed
- Liver transplantation provides survival benefit at all levels of frailty: From the Multicenter Functional Assessment in Liver Transplantation Study.| | PubMed
- The liver frailty index enhances mortality risk prediction above and beyond MELD 3.0 alone.| | PubMed
- From prognostication to therapeutics: Four key questions to accelerate the development of therapeutics for patients with acute-on-chronic liver failure.| | PubMed
- The Complex Relationship Between Pain, Mental Health, and Quality-of-Life in Patients With Cirrhosis Undergoing Liver Transplant Evaluation.| | PubMed
- Association between protein-energy malnutrition and healthcare use among adult patients after liver transplantation: A retrospective cohort study.| | PubMed
- Reply: Refining retrieval and chunking strategies for enhanced clinical reliability of large language models in liver disease.| | PubMed
- Associations between hospital-level socioeconomic patient mix and rates of central line-associated bloodstream infections in short bowel syndrome: A retrospective cohort study.| | PubMed
- Clinically relevant cut-points for changes in the Liver Frailty Index are associated with waitlist mortality in patients with cirrhosis.| | PubMed
- Caregiver-reported symptom burden and preferences for therapeutic goals in pediatric primary sclerosing cholangitis.| | PubMed
- The Liver Frailty Index: a model for establishing organ-specific frailty metrics across all solid organ transplantation.| | PubMed
- The burden of significant pain in the cirrhosis population: Risk factors, analgesic use, and impact on health care utilization and clinical outcomes.| | PubMed
- Patient-focused drug development in primary sclerosing cholangitis: Insights on patient priorities and involvement in clinical trials.| | PubMed
- Applying Metabolomics and Aptamer-based Proteomics to Determine Pathophysiologic Differences in Decompensated Cirrhosis Patients Hospitalized with Acute Kidney Injury.| | PubMed
- The influence of neighborhood income on healthcare utilization in pediatric liver transplant.| | PubMed
- Frailty, Sarcopenia, and Nutrition in Patients With Cirrhosis.| | PubMed
- Nutritional aspects of prehabilitation in adults with cirrhosis awaiting liver transplant.| | PubMed
- Outpatient mean arterial pressure: A potentially modifiable risk for acute kidney injury and death among patients with cirrhosis.| | PubMed
- Quality measures in pre-liver transplant care by the Practice Metrics Committee of the American Association for the Study of Liver Diseases.| | PubMed
- The association between mean arterial pressure and acute kidney injury reversal among patients with decompensated cirrhosis.| | PubMed
- Caregiver Perceptions of Social Risk Screening in Pediatric Liver Transplantation: From the Multicenter SOCIAL-Tx Study.| | PubMed
- Prompt Engineering for Generative Artificial Intelligence in Gastroenterology and Hepatology.| | PubMed
- Development of a liver disease-specific large language model chat interface using retrieval-augmented generation.| | PubMed
- Applying human-centered design to the construction of a cirrhosis management clinical decision support system.| | PubMed
- Outcomes of High-Grade Immune Checkpoint Inhibitor Hepatitis in Hospitalized and Nonhospitalized Patients.| | PubMed
- A modified Hospital Frailty Risk Score for patients with cirrhosis undergoing abdominal operations.| | PubMed
- Financial burden following adult liver transplantation is common and associated with adverse recipient outcomes.| | PubMed
- Prevalence and Appropriateness of Polypharmacy in Older Adults with Inflammatory Bowel Diseases.| | PubMed
- Association of biological aging with frailty and post-transplant outcomes among adults with cirrhosis.| | PubMed
- A pragmatic tool to screen for pre-transplant cognitive impairment among potential candidates for liver transplant.| | PubMed
- Caregivers' and providers' perspectives of social and medical care after pediatric liver transplant: Results from the multicenter SOCIAL-Tx study.| | PubMed
- A Comparison of a Large Language Model vs Manual Chart Review for the Extraction of Data Elements From the Electronic Health Record.| | PubMed
- Prevalence of cognitive impairment in liver transplant recipients.| | PubMed
- Barriers and Facilitators to Exercise in Older Adults Awaiting Kidney Transplantation and Their Care Partners.| | PubMed
- The liver frailty index is a predictor of healthcare utilization after liver transplantation in older adults.| | PubMed
- Association of body mass index with post-liver transplant outcomes.| | PubMed
- Development of a Liver Disease-Specific Large Language Model Chat Interface using Retrieval Augmented Generation.| | PubMed
- Association between neighborhood-based material deprivation and liver transplant waitlist registrants demographics and mortality.| | PubMed
- Neighborhood Income Is Associated with Health Care Use in Pediatric Short Bowel Syndrome.| | PubMed
- A chair-stand time of greater than 15 seconds is associated with an increased risk of death and hospitalization in cirrhosis.| | PubMed
- Ambient air pollution is associated with graft failure/death in pediatric liver transplant recipients.| | PubMed
- Association of state Medicaid expansion policies with pediatric liver transplant outcomes.| | PubMed
- Nonselective beta-blockers may lead to stage 2 acute kidney injury and waitlist mortality in child class C cirrhosis.| | PubMed
- Variation in skeletal muscle mass among patients with cirrhosis of different self-identified race/ethnicity.| | PubMed
- Structured Moderate Exercise and Biomarkers of Kidney Health in Sedentary Older Adults: The Lifestyle Interventions and Independence for Elders Randomized Clinical Trial.| | PubMed
- A comparison of large language model versus manual chart review for extraction of data elements from the electronic health record.| | PubMed
- Systematic Review and Meta-Analysis of Brief Cognitive Instruments to Evaluate Suspected Dementia in Chinese-Speaking Populations.| | PubMed
- Predicting post-liver transplant outcomes in patients with acute-on-chronic liver failure using Expert-Augmented Machine Learning.| | PubMed
- Clinical decision support and electronic interventions to improve care quality in chronic liver diseases and cirrhosis.| | PubMed
- Racial and Ethnic Disparities Among Patients Hospitalized for Acute Cholangitis in the United States.| | PubMed
- Brief PROMIS Assessment Screens for Frailty and Predicts Hospitalizations in Liver Transplant Candidates.| | PubMed
- Reply: What is the actual role of decompensated cirrhosis in the breakthrough SARS-CoV-2 infection?| | PubMed
- Novel autoantibody targets identified in patients with autoimmune hepatitis (AIH) by PhIP-Seq reveals pathogenic insights.| | PubMed
- Caregiver Burden in Adult Solid Organ Transplantation.| | PubMed
- Clinical Characteristics Associated With Posttransplant Survival Among Adults 70 Years Old or Older Undergoing Liver Transplantation.| | PubMed
- Time to embrace PROMIS-29 as the standard health-related quality of life instrument for patients with cirrhosis.| | PubMed
- Early Liver Specialist Consultation is Associated With Faster Biochemical Resolution of Severe Immune Checkpoint Inhibitor-Induced Hepatitis.| | PubMed
- Targets and study design for symptom-focused trials aimed at patients with cirrhosis: An expert consensus.| | PubMed
- Change in Platelet Count after Transjugular Intrahepatic Portosystemic Shunt Creation: An Advancing Liver Therapeutic Approaches (ALTA) Group Study.| | PubMed
- Actionable Solutions to Achieve Health Equity in Chronic Liver Disease.| | PubMed
- The tele-liver frailty index (TeLeFI): development of a novel frailty tool in patients with cirrhosis via telemedicine.| | PubMed
- Artificial intelligence-based text generators in hepatology: ChatGPT is just the beginning.| | PubMed
- Serum and plasma protein biomarkers associated with frailty in patients with cirrhosis.| | PubMed
- Breakthrough SARS-CoV-2 infection outcomes in vaccinated patients with chronic liver disease and cirrhosis: A National COVID Cohort Collaborative study.| | PubMed
- Women with cirrhosis have lower self-rated health than men.| | PubMed
- Association of Frailty With Health-Related Quality of Life in Liver Transplant Recipients.| | PubMed
- Promoting Prognostic Understanding and Health Equity for Patients With Advanced Liver Disease: Using "Best Case/Worst Case".| | PubMed
- Promoting Prognostic Understanding and Health Equity for Patients With Advanced Liver Disease: Using "Best Case/Worst Case".| | PubMed
- The impact of right atrial pressure on outcomes in patients undergoing TIPS, an ALTA group study.| | PubMed
- Introducing Norah Terrault, MD, MPH, Our 2023 AASLD President.| | PubMed
- Addressing sex-based disparities in solid organ transplantation in the United States - a conference report.| | PubMed
- CT-quantified sarcopenic visceral obesity is associated with poor transplant waitlist mortality in patients with cirrhosis.| | PubMed
- Cirrhosis Inpatients Receive More Opioids and Fewer Nonopioid Analgesics Than Patients Without Cirrhosis.| | PubMed
- Multicenter assessment of hypertension management among liver transplantation recipients.| | PubMed
- Response to: "Towards optimally replacing the current version of MELD".| | PubMed
- Predictors of Length of Stay and Mortality During Simultaneous Liver-Kidney Transplant Index Admission: Results From the US-Multicenter SLKT Consortium.| | PubMed
- Role of Oral Health, Frailty, and Minimal Hepatic Encephalopathy in the Risk of Hospitalization: A Prospective Multi-Center Cohort of Outpatients With Cirrhosis.| | PubMed
- Factors associated with cardiovascular events after simultaneous liver-kidney transplant from the US Multicenter Simultaneous Liver-Kidney Transplant Consortium.| | PubMed
- Understanding Current Limitations to Exercise Interventions After Liver Transplantation.| | PubMed
- Which preoperative assessment modalities best identify patients who are suitable for enhanced recovery after liver transplantation? A systematic review of the literature and expert panel recommendations.| | PubMed
- Personality Traits in Patients With Cirrhosis Are Different From Those of the General Population and Impact Likelihood of Liver Transplantation.| | PubMed
- Leveraging a New ICD-10 Diagnosis Code to Characterize Hospitalized Patients With Primary Sclerosing Cholangitis.| | PubMed
- Association of serum metabolites and gut microbiota at hospital admission with nosocomial infection development in patients with cirrhosis.| | PubMed
- Novel approaches are needed to study social determinants of health in liver transplantation.| | PubMed
- Medical Need and Transplant Accessibility-Reply.| | PubMed
- Hepatic and renal function impact concentrations of plasma biomarkers of neuropathology.| | PubMed
- Breakthrough SARS-CoV-2 Infection Outcomes in Vaccinated Patients with Chronic Liver Disease and Cirrhosis: A National COVID Cohort Collaborative Study.| | PubMed
- Financial burden in adults with chronic liver disease: A scoping review.| | PubMed
- Burden of early hospitalization after simultaneous liver-kidney transplantation: Results from the US Multicenter SLKT Consortium.| | PubMed
- The digital determinants of liver disease.| | PubMed
- Caregiver perspectives on the everyday medical and social needs of long-term pediatric liver transplant patients.| | PubMed
- "Beyond MELD" - Emerging strategies and technologies for improving mortality prediction, organ allocation and outcomes in liver transplantation.| | PubMed
- Conceptualizing a Traditional Chinese Medicine and Pathology of Arousal Diagnostic and Pathophysiological Framework for Postacute Sequelae of COVID-19.| | PubMed
- Improvement in Long-COVID Symptoms Using Acupuncture: A Case Study.| | PubMed
- Sarcopenic visceral obesity is associated with increased post-liver transplant mortality in acutely ill patients with cirrhosis.| | PubMed
- Loneliness in adults awaiting liver transplantation at 7 U.S. transplant centers.| | PubMed
- A review of racial, socioeconomic, and geographic disparities in pediatric liver transplantation.| | PubMed
- Medical Need, Financial Resources, and Transplant Accessibility.| | PubMed
- Admission Serum Metabolites and Thyroxine Predict Advanced Hepatic Encephalopathy in a Multicenter Inpatient Cirrhosis Cohort.| | PubMed
- Variability in serum creatinine is associated with waitlist and post-liver transplant mortality in patients with cirrhosis.| | PubMed
- Improving the Model for End-Stage Liver Disease with sodium by incorporating kidney dysfunction types.| | PubMed
- The bidirectional relationship between nonalcoholic fatty liver disease and sarcopenia.| | PubMed
- Acute-on-Chronic Liver Failure.| | PubMed
- Association of Primary Care Shortage Areas with Adverse Outcomes after Pediatric Liver Transplant.| | PubMed
- Perioperative Delta Sodium and Post-Liver Transplant Neurological Complications in Liver Transplant Recipients.| | PubMed
- Top Ten Tips Palliative Care Clinicians Should Know About Solid Organ Transplantation.| | PubMed
- Osmotic Demyelination Syndrome in Hospitalized Patients With Cirrhosis: Analysis of the National Inpatient Sample (NIS).| | PubMed
- Implicit bias and the gender inequity in liver transplantation.| | PubMed
- Acute-on-Chronic Liver Failure Clinical Guidelines.| | PubMed
- Prognosis of hospitalized patients with cirrhosis and acute kidney disease.| | PubMed
- Reply.| | PubMed
- Long-Term Opioid Use Among Veterans with Cirrhosis: High-Dose Prescriptions in an Exceedingly High-Risk Population.| | PubMed
- The 5Ms of Geriatrics in Gastroenterology: The Path to Creating Age-Friendly Care for Older Adults With Inflammatory Bowel Diseases and Cirrhosis.| | PubMed
- Frailty, mortality, and health care utilization after liver transplantation: From the Multicenter Functional Assessment in Liver Transplantation (FrAILT) Study.| | PubMed
- Racial/ethnic disparities in wait-list outcomes are only partly explained by socioeconomic deprivation among children awaiting liver transplantation.| | PubMed
- Frailty is associated with increased risk of cirrhosis disease progression and death.| | PubMed
- Frailty is strongly associated with self-reported symptom burden among patients with cirrhosis.| | PubMed
- An Analysis of Free-Text Refusals as an Indicator of Readiness to Accept Organ Offers in Liver Transplantation.| | PubMed
- The Prediction of In-Hospital Mortality in Decompensated Cirrhosis with Acute-on-Chronic Liver Failure.| | PubMed
- Sex-based Disparities in Hepatocellular Carcinoma Recurrence After Liver Transplantation.| | PubMed
- Pilot Randomized Controlled Trial of an Advance Care Planning Video Decision Tool for Patients With Advanced Liver Disease.| | PubMed
- Frailty and the Risk of Acute Kidney Injury Among Patients With Cirrhosis.| | PubMed
- Frailty and Risk of Serious Infections in Biologic-treated Patients With Inflammatory Bowel Diseases.| | PubMed
- Addressing Social Adversity to Improve Outcomes for Children After Liver Transplant.| | PubMed
- Outcomes After TIPS for Ascites and Variceal Bleeding in a Contemporary Era-An ALTA Group Study.| | PubMed
- Thinking Ahead: Advance Care Planning for Patients With Cirrhosis.| | PubMed
- Malnutrition, Frailty, and Sarcopenia in Patients With Cirrhosis: 2021 Practice Guidance by the American Association for the Study of Liver Diseases.| | PubMed
- Correcting the sex disparity in access to liver transplantation: Lest perfect be the enemy of better.| | PubMed
- Cognitive Impairment and Physical Frailty in Patients With Cirrhosis.| | PubMed
- Temporal Trends and Evolving Outcomes After Simultaneous Liver-Kidney Transplantation: Results from the US SLKT Consortium.| | PubMed
- Symptom Burden Is Associated with Increased Emergency Department Utilization among Patients with Cirrhosis.| | PubMed
- Inpatient Frailty Assessment Is Feasible and Predicts Nonhome Discharge and Mortality in Decompensated Cirrhosis.| | PubMed
- Association Between Kidney Dysfunction Types and Mortality Among Hospitalized Patients with Cirrhosis.| | PubMed
- Outcomes of SARS-CoV-2 Infection in Patients With Chronic Liver Disease and Cirrhosis: A National COVID Cohort Collaborative Study.| | PubMed
- The relationship between frailty and cirrhosis etiology: From the Functional Assessment in Liver Transplantation (FrAILT) Study.| | PubMed
- Admission Urinary and Serum Metabolites Predict Renal Outcomes in Hospitalized Patients With Cirrhosis.| | PubMed
- Sarcopenia and frailty in decompensated cirrhosis.| | PubMed
- Developing Priorities for Palliative Care Research in Advanced Liver Disease: A Multidisciplinary Approach.| | PubMed
- Visceral Adipose Tissue Inflammation and Radiographic Visceral-to-Subcutaneous Adipose Tissue Ratio in Patients with Cirrhosis.| | PubMed
- Outcomes of SARS-CoV-2 Infection in Patients with Chronic Liver Disease and Cirrhosis: a N3C Study.| | PubMed
- Association of Cognitive Function Screening Results with Adherence and Performance in a Pedometer-Based Intervention.| | PubMed
- Advance Care Planning in Liver Transplant-Preparing for Both Life and Death.| | PubMed
- Renal Outcomes After Simultaneous Liver-Kidney Transplantation: Results from the US Multicenter Simultaneous Liver-Kidney Transplantation Consortium.| | PubMed
- A Multicenter Pilot Randomized Clinical Trial of a Home-Based Exercise Program for Patients With Cirrhosis: The Strength Training Intervention (STRIVE).| | PubMed
- Early Kidney Allograft Failure After Simultaneous Liver-kidney Transplantation: Evidence for Utilization of the Safety Net?| | PubMed
- Patterns of Inpatient Opioid Use and Related Adverse Events Among Patients With Cirrhosis: A Propensity-Matched Analysis.| | PubMed
- A Methodology to Generate Longitudinally Updated Acute-On-Chronic Liver Failure Prognostication Scores From Electronic Health Record Data.| | PubMed
- Center variation in long-term outcomes for socioeconomically deprived children.| | PubMed
- Renal Recovery and Mortality Risk among Patients with Hepatorenal Syndrome Receiving Chronic Maintenance Dialysis.| | PubMed
- Association of Frailty and Sex With Wait List Mortality in Liver Transplant Candidates in the Multicenter Functional Assessment in Liver Transplantation (FrAILT) Study.| | PubMed
- Assessment of the Frail Patient With End-Stage Liver Disease: A Practical Overview of Sarcopenia, Physical Function, and Disability.| | PubMed
- Implementing a Height-Based Rule for the Allocation of Pediatric Donor Livers to Adults: A Liver Simulated Allocation Model Study.| | PubMed
- Low Predictability of Readmissions and Death Using Machine Learning in Cirrhosis.| | PubMed
- Evaluating the Associations Between the Liver Frailty Index and Karnofsky Performance Status With Waitlist Mortality.| | PubMed
- National Early Career Transplant Hepatologist Survey: Compensation, Burnout, and Job Satisfaction.| | PubMed
- Nonalcoholic Fatty Liver Disease and Diabetes Mellitus Are Associated With Post-Transjugular Intrahepatic Portosystemic Shunt Renal Dysfunction: An Advancing Liver Therapeutic Approaches Group Study.| | PubMed
- Increased Risk of ACLF and Inpatient Mortality in Hospitalized Patients with Cirrhosis and Hepatic Hydrothorax.| | PubMed
- Kefir Peptides Prevent Estrogen Deficiency-Induced Bone Loss and Modulate the Structure of the Gut Microbiota in Ovariectomized Mice.| | PubMed
- Identifying an Optimal Liver Frailty Index Cutoff to Predict Waitlist Mortality in Liver Transplant Candidates.| | PubMed
- Outcomes of Liver Transplantation Among Older Recipients With Nonalcoholic Steatohepatitis in a Large Multicenter US Cohort: the Re-Evaluating Age Limits in Transplantation Consortium.| | PubMed
- Unforeseen consequences of the COVID pandemic.| | PubMed
- Progression of Stage 2 and 3 Acute Kidney Injury in Patients With Decompensated Cirrhosis and Ascites.| | PubMed
- Neighborhood socioeconomic deprivation, racial segregation, and organ donation across 5 states.| | PubMed
- Association of motivations and barriers with participation and performance in a pedometer-based intervention.| | PubMed
- Psychological contributors to the frail phenotype: The association between resilience and frailty in patients with cirrhosis.| | PubMed
- Serum Levels of Metabolites Produced by Intestinal Microbes and Lipid Moieties Independently Associated With Acute-on-Chronic Liver Failure and Death in Patients With Cirrhosis.| | PubMed
- Time for Action to Address the Persistent Sex-Based Disparity in Liver Transplant Access.| | PubMed
- Frailty as an Immune-Mediated Condition That Leads to an Increased Risk of Acute Cellular Rejection in Liver Transplant Recipients.| | PubMed
- Liver Transplant Survivorship.| | PubMed
- Low Rates of Advance Care Planning (ACP) Discussions Despite Readiness to Engage in ACP Among Liver Transplant Candidates.| | PubMed
- Multicenter Study of Age, Frailty, and Waitlist Mortality Among Liver Transplant Candidates.| | PubMed
- Aggressive utilization of liver allografts: Improved outcomes over time.| | PubMed
- Women who undergo liver transplant have longer length of stay post-transplant compared with men.| | PubMed
- Insurance Status But Not Race and Ethnicity Are Associated With Outcomes in a Large Hospitalized Cohort of Patients With Cirrhosis.| | PubMed
- Physical Function, Physical Activity, and Quality of Life After Liver Transplantation.| | PubMed
- Association of Karnofsky Performance Status with waitlist mortality among older and younger adults awaiting kidney transplantation.| | PubMed
- Chronic Kidney Disease in Liver Transplant Candidates: A Rising Burden Impacting Post-Liver Transplant Outcomes.| | PubMed
- Changes in frailty are associated with waitlist mortality in patients with cirrhosis.| | PubMed
- Effect of a pedometer-based walking intervention on body composition in patients with ESRD: a randomized controlled trial.| | PubMed
- Underutilization of Hospice in Inpatients with Cirrhosis: The NACSELD Experience.| | PubMed
- Neighborhood socioeconomic deprivation is associated with worse patient and graft survival following pediatric liver transplantation.| | PubMed
- Frailty Is Associated With Increased Rates of Acute Cellular Rejection Within 3 Months After Liver Transplantation.| | PubMed
- A Comprehensive Review of Outcome Predictors in Low MELD Patients.| | PubMed
- Response to "Reply to: 'The decreasing predictive power of MELD in an era of changing etiology of liver disease'".| | PubMed
- Gender Differences Among Patients Hospitalized With Cirrhosis in the United States.| | PubMed
- Split liver transplantation is utilized infrequently and concentrated at few transplant centers in the United States.| | PubMed
- Association Between Liver Transplant Wait-list Mortality and Frailty Based on Body Mass Index.| | PubMed
- Sex Differences in the Association Between Frailty and Sarcopenia in Patients With Cirrhosis.| | PubMed
- Differential Impact of Age Among Liver Transplant Candidates With and Without Hepatocellular Carcinoma.| | PubMed
- Identifying a clinically relevant cutoff for height that is associated with a higher risk of waitlist mortality in liver transplant candidates.| | PubMed
- Sarcopenia Predicts Post-transplant Mortality in Acutely Ill Men Undergoing Urgent Evaluation and Liver Transplantation.| | PubMed
- Frailty and the Burden of Concurrent and Incident Disability in Patients With Cirrhosis: A Prospective Cohort Study.| | PubMed
- Hospitalized Women With Cirrhosis Have More Nonhepatic Comorbidities and Associated Complications Than Men.| | PubMed
- Review article: impact of exercise on physical frailty in patients with chronic liver disease.| | PubMed
- The decreasing predictive power of MELD in an era of changing etiology of liver disease.| | PubMed
- A North American Expert Opinion Statement on Sarcopenia in Liver Transplantation.| | PubMed
- Barriers to ideal outcomes after pediatric liver transplantation.| | PubMed
- Nosocomial Infections Are Frequent and Negatively Impact Outcomes in Hospitalized Patients With Cirrhosis.| | PubMed
- Impact of Muscle Gain after Transjugular Intrahepatic Portosystemic Shunt Creation on Patients Awaiting Liver Transplantation.| | PubMed
- Frailty in liver transplantation: An expert opinion statement from the American Society of Transplantation Liver and Intestinal Community of Practice.| | PubMed
- Changes in Simultaneous Liver-kidney Transplant Allocation Policy May Impact Postliver Transplant Outcomes.| | PubMed
- Split-Liver Allocation: An Underused Opportunity to Expand Access to Liver Transplantation.| | PubMed
- Targets to improve quality of care for patients with hepatic encephalopathy: data from a multi-centre cohort.| | PubMed
- The Range and Reproducibility of the Liver Frailty Index.| | PubMed
- Impact of Chronic Kidney Disease on Outcomes in Cirrhosis.| | PubMed
- Outcomes in Patients With Cirrhosis on Primary Compared to Secondary Prophylaxis for Spontaneous Bacterial Peritonitis.| | PubMed
- Outcomes After Listing for Liver Transplant in Patients With Acute-on-Chronic Liver Failure: The Multicenter North American Consortium for the Study of End-Stage Liver Disease Experience.| | PubMed
- Women on the liver transplantation waitlist are at increased risk of hospitalization compared to men.| | PubMed
- Deceased Pediatric Donor Livers: How Current Policy Drives Allocation and Transplantation.| | PubMed
- Association Between Renal Function Pattern and Mortality in Patients With Cirrhosis.| | PubMed
- Frailty Associated With Waitlist Mortality Independent of Ascites and Hepatic Encephalopathy in a Multicenter Study.| | PubMed
- Functional status at listing predicts waitlist and posttransplant mortality in pediatric liver transplant candidates.| | PubMed
- Report from the American Society of Transplantation on frailty in solid organ transplantation.| | PubMed
- Sex hormone levels by presence and severity of cirrhosis in women with chronic hepatitis C virus infection.| | PubMed
- How I Approach It: Improving Nutritional Status in Patients With Cirrhosis.| | PubMed
- Poor performance of psoas muscle index for identification of patients with higher waitlist mortality risk in cirrhosis.| | PubMed
- Acute-on-Chronic Liver Failure: Getting Ready for Prime Time?| | PubMed
- Beta-blockers and physical frailty in patients with end-stage liver disease.| | PubMed
- Patient and Caregiver Attitudes and Practices of Exercise in Candidates Listed for Liver Transplantation.| | PubMed
- Determination of Free 25(OH)D Concentrations and Their Relationships to Total 25(OH)D in Multiple Clinical Populations.| | PubMed
- Association Between Intestinal Microbiota Collected at Hospital Admission and Outcomes of Patients With Cirrhosis.| | PubMed
- People who experience seclusion in adult mental health inpatient services: An examination of health of the nation outcome scales scores.| | PubMed
- "Normal" Creatinine Levels Predict Persistent Kidney Injury and Waitlist Mortality in Outpatients With Cirrhosis.| | PubMed
- The Impact of Albumin Use on Resolution of Hyponatremia in Hospitalized Patients With Cirrhosis.| | PubMed
- Receipt of a pediatric liver offer as the first offer reduces waitlist mortality for adult women.| | PubMed
- Assessment of the spectrum of hepatic encephalopathy: A multicenter study.| | PubMed
- Reply.| | PubMed
- NACSELD acute-on-chronic liver failure (NACSELD-ACLF) score predicts 30-day survival in hospitalized patients with cirrhosis.| | PubMed
- Physical frailty after liver transplantation.| | PubMed
- Association of Cardiac Abnormalities to the Frail Phenotype in Cirrhotic Patients on the Waitlist: From the Functional Assessment in Liver Transplantation Study.| | PubMed
- Primary healthcare utilisation among adults with mood and anxiety disorders: an analysis of the New Zealand Health Survey.| | PubMed
- A2 liver transplantation across the ABO barrier: Increasing options in the donor pool?| | PubMed
- Sex-based disparities in delisting for being "too sick" for liver transplantation.| | PubMed
- Prediction of Fungal Infection Development and Their Impact on Survival Using the NACSELD Cohort.| | PubMed
- The Liver Frailty Index Improves Mortality Prediction of the Subjective Clinician Assessment in Patients With Cirrhosis.| | PubMed
- Opioid and opioid substitution therapy in liver transplant candidates: A survey of center policies and practices.| | PubMed
- Liver Transplantation in the Obese Cirrhotic Patient.| | PubMed
- Transplant for the very sick: No limitations in donor quality?| | PubMed
- Analysis of Liver Offers to Pediatric Candidates on the Transplant Wait List.| | PubMed
- Development of a novel frailty index to predict mortality in patients with end-stage liver disease.| | PubMed
- Race/ethnicity is associated with ABO-nonidentical liver transplantation in the United States.| | PubMed
- Reporting functional status in UNOS: The weakness of the Karnofsky Performance Status Scale.| | PubMed
- A multicenter study to define sarcopenia in patients with end-stage liver disease.| | PubMed
- Cost-Effectiveness of Direct-Acting Antiviral Treatment in Hepatitis C-Infected Liver Transplant Candidates With Compensated Cirrhosis and Hepatocellular Carcinoma.| | PubMed
- Disability in patients with end-stage liver disease: Results from the functional assessment in liver transplantation study.| | PubMed
- Frailty is independently associated with increased hospitalisation days in patients on the liver transplant waitlist.| | PubMed
- A framework to determine when liver transplantation is futile.| | PubMed
- Clinical Liver Disease| UCSF Research Profile
- Short Physical Performance Battery and all-cause mortality: systematic review and meta-analysis.| | PubMed
- Factors Associated with Medication Non-adherence in Patients with End-Stage Liver Disease.| | PubMed
- Editorial: Advancing Adoption of Frailty to Improve the Care of Patients with Cirrhosis: Time for a Consensus on a Frailty Index.| | PubMed
- Performance-Based Measures Associate With Frailty in Patients With End-Stage Liver Disease.| | PubMed
- Acute Liver Failure Secondary to Hemophagocytic Lymphohistiocytosis during Pregnancy.| | PubMed
- Hepatic Encephalopathy Is Associated With Mortality in Patients With Cirrhosis Independent of Other Extrahepatic Organ Failures.| | PubMed
- Underutilization of palliative care services in the liver transplant population.| | PubMed
- A Comparison of Muscle Function, Mass, and Quality in Liver Transplant Candidates: Results From the Functional Assessment in Liver Transplantation Study.| | PubMed
- ABO-Nonidentical Liver Transplantation in the United States.| | PubMed
- Defining the threshold for too sick for transplant.| | PubMed
- Response to clinical assessments of health status as a potential marker to identify patients who are too sick to undergo transplantation.| | PubMed
- Functional decline in patients with cirrhosis awaiting liver transplantation: Results from the functional assessment in liver transplantation (FrAILT) study.| | PubMed
- Functional impairment in older liver transplantation candidates: From the functional assessment in liver transplantation study.| | PubMed
- Outcomes for liver transplant candidates listed with low model for end-stage liver disease score.| | PubMed
- Kidney Failure and Liver Allocation: Current Practices and Potential Improvements.| | PubMed
- Decision support for organ offers in liver transplantation.| | PubMed
- Hepatitis C genotype influences post-liver transplant outcomes.| | PubMed
- Total 25(OH) vitamin D, free 25(OH) vitamin D and markers of bone turnover in cirrhotics with and without synthetic dysfunction.| | PubMed
- Clinician assessments of health status predict mortality in patients with end-stage liver disease awaiting liver transplantation.| | PubMed
- Bone Mineral Density, Bone Turnover, and Systemic Inflammation in Non-cirrhotics with Chronic Hepatitis C.| | PubMed
- Role of delta-aminolevulinic acid in the symptoms of acute porphyria.| | PubMed
- Combined effects of recipient age and model for end-stage liver disease score on liver transplantation outcomes.| | PubMed
- The octogenarian donor: can the liver be "younger than stated age"?| | PubMed
- Expanded criteria donors.| | PubMed
- Frailty predicts waitlist mortality in liver transplant candidates.| | PubMed
- A comparison of measured and calculated free 25(OH) vitamin D levels in clinical populations.| | PubMed
- Variability in free 25(OH) vitamin D levels in clinical populations.| | PubMed
- Reducing infection transmission in solid organ transplantation through donor nucleic acid testing: a cost-effectiveness analysis.| | PubMed
- Offer patterns of nationally placed livers by donation service area.| | PubMed
- Center competition and outcomes following liver transplantation.| | PubMed
- Sudden onset vision loss in an 8-year-old female with McCune-Albright syndrome.| | PubMed
- An examination of liver offers to candidates on the liver transplant wait-list.| | PubMed
- Recipient-donor race mismatch for African American liver transplant patients with chronic hepatitis C.| | PubMed
- Risk of advanced fibrosis with grafts from hepatitis C antibody-positive donors: a multicenter cohort study.| | PubMed
- Effects of ethnicity and socioeconomic status on survival and severity of fibrosis in liver transplant recipients with hepatitis C virus.| | PubMed
- Patient, center and geographic characteristics of nationally placed livers.| | PubMed
- Hepatic steatosis at 1 year is an additional predictor of subsequent fibrosis severity in liver transplant recipients with recurrent hepatitis C virus.| | PubMed
- Hepatitis C virus-infected women have a higher risk of advanced fibrosis and graft loss after liver transplantation than men.| | PubMed
- Gender differences in liver donor quality are predictive of graft loss.| | PubMed
- Height contributes to the gender difference in wait-list mortality under the MELD-based liver allocation system.| | PubMed
- Lessons from HIV therapy applied to viral hepatitis therapy: summary of a workshop.| | PubMed
- A novel housestaff educational model for quaternary-care patients at an academic health center.| | PubMed
- Resource utilization of living donor versus deceased donor liver transplantation is similar at an experienced transplant center.| | PubMed