Biography
Dr. Leard is Associate Dean for Continuing Medical Education for the UCSF School of Medicine and Vice Chief of Clinical Operations for the UCSF Division of Pulmonary, Critical Care, Allergy and Sleep Medicine. Her major academic interests include Medical Education, Lung Transplantation and Lung Cancer. She cares for patients on the Advanced Lung Disease Service at UCSF Moffitt-Long Hospital, and sees patients at the Mt. Zion Comprehensive Cancer Center.
She is a past president of the California Thoracic Society. She serves on Item Review Committees for the National Board of Medical Educators and is an Editorial Board Consultant for the Journal of Heart and Lung Transplantation. She is Vice Chair (2023-2024) of the Committee on Academic Personnel -Gold Committee.
Videos
Awards & Honors
Award | Conferred By | Date |
---|---|---|
V. Courtney Broaddus Award for Leadership and Service | UCSF | 2022 |
Academy of Medical Educators | UCSF | 2011 |
Michael S. Stulbarg Outstanding Teaching Award | UCSF | 2007 |
Education
Institution | Degree | Dept or School | End Date |
---|---|---|---|
University of California | Relationship-Centered Communication Skills for Racial Equity in Healthcare | 2019 | |
University of California | Diversity, Equity, and Inclusion Champion Training | 2018 | |
University of California | Fellowship | Lung Transplantation | 2006 |
University of California | Fellowship | Pulmonary and Critical Care Medicine | 2005 |
University of Texas Southwestern | Internship & Residency | Internal Medicine | 2001 |
University of California | M.D. | School of Medicine | 1998 |
Board Certifications
American Board of Internal Medicine - Internal Medicine
American Board of Internal Medicine - Critical Care Medicine
American Board of Internal Medicine - Pulmonary Disease
Clinical Expertise
Malignant Mesothelioma
Non-Small Cell Lung Cancer
Small Cell Lung Cancer
Lung Cancer Screening
Pulmonary (lung) Metastases
Tracheal/Bronchial Stent Placement
Transbronchial Needle Aspiration (TBNA)
Endobronchial Ultrasound (EBUS)
Tracheobronchial Dilatation
Program Affiliations
Thoracic Oncology Progam
Lung Transplant Program
Lung Cancer Screening Program
Research Narrative
Dr. Leard's current research interests include (1) Assessment of the role of Donor Specific Antibodies in the development of Bronchiolitis obliterans, (2) Bronchoscopy Complications, and (3) Lung Cancer Screening.
Research Interests
Lung Cancer Screening & Surveillance
Complications of Lung Transplantation
Publications
- Small airway brush gene expression predicts chronic lung allograft dysfunction and mortality.| | PubMed
- Macrophage and CD8 T cell discordance are associated with acute lung allograft dysfunction progression.| | PubMed
- CCR5 drives NK cell-associated airway damage in pulmonary ischemia-reperfusion injury.| | PubMed
- Decreased Lymphocytic Bronchitis Severity in the Era of Azithromycin Prophylaxis.| | PubMed
- Development of the Lung Transplant Frailty Scale (LT-FS).| | PubMed
- Design and implementation of a digital health home spirometry intervention for remote monitoring of lung transplant function.| | PubMed
- The Lung Allocation Score Remains Inequitable for Patients with Pulmonary Arterial Hypertension, Even after the 2015 Revision.| | PubMed
- CD16+ natural killer cells in bronchoalveolar lavage are associated with antibody-mediated rejection and chronic lung allograft dysfunction.| | PubMed
- NKG2D receptor activation drives primary graft dysfunction severity and poor lung transplantation outcomes.| | PubMed
- NCCN Guidelines® Insights: Lung Cancer Screening, Version 1.2022.| | PubMed
- Response to selection of lung transplant candidates: A pediatric perspective on the ISHLT consensus document.| | PubMed
- Depressive symptoms in lung transplant recipients: trajectory and association with mortality and allograft dysfunction.| | PubMed
- Inflammation on bronchoalveolar lavage cytology is associated with decreased chronic lung allograft dysfunction-free survival.| | PubMed
- A survey of use of mTOR inhibitors in patients with lymphangioleiomyomatosis listed for lung transplant.| | PubMed
- What's in a name: The importance of lung transplant at Cystic Fibrosis Foundation Accredited Care Centers for patients with Cystic Fibrosis.| | PubMed
- Lung Allograft Epithelium DNA Methylation Age Is Associated With Graft Chronologic Age and Primary Graft Dysfunction.| | PubMed
- Construct and Predictive Validity of Sarcopenia in Lung Transplant Candidates.| | PubMed
- Perceptions Around Lung Transplant-Associated Hypogammaglobulinemia.| | PubMed
- Consensus document for the selection of lung transplant candidates: An update from the International Society for Heart and Lung Transplantation.| | PubMed
- The association of post-operative delirium with patient-reported outcomes and mortality after lung transplantation.| | PubMed
- Lung transplantation from swimming pool drowning victims: A case series.| | PubMed
- Type-1 immunity and endogenous immune regulators predominate in the airway transcriptome during chronic lung allograft dysfunction.| | PubMed
- Chronic lung allograft dysfunction small airways reveal a lymphocytic inflammation gene signature.| | PubMed
- Primary graft dysfunction attenuates improvements in health-related quality of life after lung transplantation, but not disability or depression.| | PubMed
- Cystic Fibrosis Lung Transplant Recipients Have Suppressed Airway Interferon Responses during Pseudomonas Infection.| | PubMed
- Frailty after lung transplantation is associated with impaired health-related quality of life and mortality.| | PubMed
- Improvements in frailty contribute to substantial improvements in quality of life after lung transplantation in patients with cystic fibrosis.| | PubMed
- Mitochondrial DNA Stimulates TLR9-Dependent Neutrophil Extracellular Trap Formation in Primary Graft Dysfunction.| | PubMed
- Tacrolimus trough monitoring guided by mass spectrometry without accounting for assay differences is associated with acute kidney injury in lung transplant recipients.| | PubMed
- Management and clinical outcomes after lung transplantation in patients with pre-transplant Mycobacterium abscessus infection: A single center experience.| | PubMed
- Gene signatures common to allograft rejection are associated with lymphocytic bronchitis.| | PubMed
- Frailty trajectories in adult lung transplantation: A cohort study.| | PubMed
- Wildfires Disaster Guidance: Tips for Staying Healthy during Wildfires.| | PubMed
- Pirfenidone-Induced Sarcoid-Like Reaction: A Novel Complication.| | PubMed
- Human leukocyte antigens antibodies after lung transplantation: Primary results of the HALT study.| | PubMed
- Lung Cancer Screening, Version 3.2018, NCCN Clinical Practice Guidelines in Oncology.| | PubMed
- Improvement in patient-reported outcomes after lung transplantation is not impacted by the use of extracorporeal membrane oxygenation as a bridge to transplantation.| | PubMed
- ISHLT Consensus Statement on adult and pediatric airway complications after lung transplantation: Definitions, grading system, and therapeutics.| | PubMed
- Refining Low Physical Activity Measurement Improves Frailty Assessment in Advanced Lung Disease and Survivors of Critical Illness.| | PubMed
- Donor-Reactive Regulatory T Cell Frequency Increases During Acute Cellular Rejection of Lung Allografts.| | PubMed
- Lung transplantation after prior cardiothoracic surgery: To transplant or not to transplant.| | PubMed
- Acquired acanthosis nigricans with tripe palms in a patient with interstitial lung disease.| | PubMed
- Frailty Phenotypes, Disability, and Outcomes in Adult Candidates for Lung Transplantation.| | PubMed
- Prolonged Barium-Impaction Ileus in Two Lung Transplant Recipients With Systemic Sclerosis: Case Report.| | PubMed
- Lung transplantation for hypersensitivity pneumonitis.| | PubMed
- Clinical outcomes of lung transplant recipients with telomerase mutations.| | PubMed
- Lung cancer screening, version 1.2015: featured updates to the NCCN guidelines.| | PubMed
- The feasibility of lung transplantation in HIV-seropositive patients.| | PubMed
- Development and validation of a lung transplant-specific disability questionnaire.| | PubMed
- A thematic analysis of quality of life in lung transplant: the existing evidence and implications for future directions.| | PubMed
- Scedosporium prolificans pericarditis and mycotic aortic aneurysm in a lung transplant recipient receiving voriconazole prophylaxis.| | PubMed
- Rhinovirus and other respiratory viruses exert different effects on lung allograft function that are not mediated through acute rejection.| | PubMed
- Rapidly progressive pulmonary venoocclusive disease in young women taking oral contraceptives.| | PubMed
- Lung cancer screening.| | PubMed
- Use of sublingual tacrolimus in lung transplant recipients.| | PubMed
- An analysis of potential risk factors for early complications from fiberoptic bronchoscopy in lung transplant recipients.| | PubMed
- The impact of pretransplant mechanical ventilation on short- and long-term survival after lung transplantation.| | PubMed
- Management of recurrent airway strictures in lung transplant recipients using AERO covered stents.| | PubMed
- Supratherapeutic anticoagulation from low-molecular-weight heparin in lung transplant recipients.| | PubMed
- Progression of native lung fibrosis in lung transplant recipients with idiopathic pulmonary fibrosis.| | PubMed
- Lung transplantation in patients with connective tissue disorders and esophageal dysmotility.| | PubMed
- Fatal diffuse alveolar damage in two lung transplant patients treated with cetuximab.| | PubMed
- Antireflux surgery for patients with end-stage lung disease before and after lung transplantation.| | PubMed
- Lung transplantation for pulmonary metastases and radiation-induced pulmonary fibrosis after radioactive iodine ablation of extensive lung metastases from papillary thyroid carcinoma.| | PubMed
- Gastroesophageal reflux in patients with idiopathic pulmonary fibrosis referred for lung transplantation.| | PubMed
- Prevalence of delayed gastric emptying and gastroesophageal reflux in patients with end-stage lung disease.| | PubMed
- The prevalence of distal and proximal gastroesophageal reflux in patients awaiting lung transplantation.| | PubMed
- Mesothelial cell proliferation and apoptosis.| | PubMed