Shant Vartanian, MD | UCSF Department of Surgery

Biography

The enhanced longevity of patients living with chronic HIV infection has resulted in an increasing burden of chronic diseases, and while there is growing evidence that HIV infected patients at risk for coronary artery disease at rates of up to two fold higher than the uninfected, the significance of chronic HIV infection in the peripheral vasculature is largely unknown. My principle clinical appointment has been at San Francisco General Hospital, which was at the center of the HIV epidemic in the 1980’s. This research program grew in response to the burden of disease witnessed in clinic on a weekly basis. A cursory review of the literature will show how little we understand about the link between HIV infection and peripheral arterial disease (PAD). My research focus is to bridge the gap in our understanding of the contribution of HIV infection to the development of PAD using a combination of clinical, epidemiological and translational research methodologies.

Education

Institution	Degree	Dept or School	End Date
University of California, San Francisco	Fellow, Vascular Surgery		2012
University of California, San Francisco	Vascular Surgery Fellowship	School of Medicine	2012
University of Calfornia, San Francisco	General Surgery Residency	School of Medicine	2010
University of California, San Francisco	Chief Resident, General Surgery		2010
University of California, San Francisco	Resident, General Surgery		2009
University of California, San Francisco	Post-Doctoral Research Fellow, Laboratory for Acce		2007
University of California, San Francisco	Intern, General Surgery		2004
St. Louis University	M.D.	School of Medicine	2003

Board Certifications

American Board of Surgery, 2011

Clinical Expertise

Aortic Dissection

Abdominal Aortic Aneurysm

Carotid Artery Disease

Complex Limb Revascularization

Critical Limb Ischemia

Diabetic Vascular Disease

Dialysis Access

Endovascular Aneurysm Repair

Mesenteric Artery Disease

Peripheral Artery Disease

Thoracic Aortic Aneurysm

Thoracic Outlet Syndrome

Research Narrative

Dr. Vartanian is interested in comparing the effectiveness of endovascular treatments for peripheral arterial disease. By understanding the safety, effectiveness, and cost of each intervention, the aim of the research is to assist patients and clinicians in making informed decisions about treatment options.

Research Interests

Comparative effectiveness of endovacular interventions for lower extremity arterial disease
Endovascular interventions for acute and chronic aortic conditions

Publications

MOST RECENT PUBLICATIONS FROM A TOTAL OF 42

Relevance of BEST-CLI trial endpoints in a tertiary care limb preservation program.
Liu IH, El Khoury R, Hiramoto JS, Gasper WJ, Schneider PA, Vartanian SM, Conte MS| 2024-02-23 | PubMed
Renal Embolization-Induced Uremic Swine Model for Assessment of Next-Generation Implantable Hemodialyzers.
Moyer J, Wilson MW, Sorrentino TA, Santandreu A, Chen C, Hu D, Kerdok A, Porock E, Wright N, Ly J, Blaha C, Frassetto LA, Fissell WH, Vartanian SM, Roy S| 2023-09-04 | PubMed
Feasibility of an implantable bioreactor for renal cell therapy using silicon nanopore membranes.
Kim EJ, Chen C, Gologorsky R, Santandreu A, Torres A, Wright N, Goodin MS, Moyer J, Chui BW, Blaha C, Brakeman P, Vartanian S, Tang Q, David Humes H, Fissell WH, Roy S| 2023-08-29 | PubMed
Patients with abdominal aortic aneurysms have reduced levels of microRNA 122-5p in circulating exosomes.
Lopez JL, Ramirez JL, Phu TA, Duong P, Bouchareychas L, Kuhrau CR, Lin PY, Eckalbar WL, Barczak AJ, Rudolph JD, Maliskova L, Conte MS, Vartanian SM, Raffai RL, Oskowitz AZ| 2023-02-14 | PubMed
Presenting limb severity is associated with long-term outcomes after infrainguinal revascularization for chronic limb-threatening ischemia.
Liu IH, El Khoury R, Wu B, Gasper WJ, Schneider PA, Hiramoto JS, Vartanian SM, Conte MS| 2022-12-27 | PubMed
Characterization of human islet function in a convection-driven intravascular bioartificial pancreas.
Santandreu AG, Taheri-Tehrani P, Feinberg B, Torres A, Blaha C, Shaheen R, Moyer J, Wright N, Szot GL, Fissell WH, Vartanian S, Posselt A, Roy S| 2022-12-14 | PubMed
Pedal arterial calcification score is associated with hemodynamic change and major amputation after infrainguinal revascularization for chronic limb-threatening ischemia.
Liu IH, Wu B, Krepkiy V, El Khoury R, Ferraresi R, Reyzelman AM, Hiramoto JS, Schneider PA, Conte MS, Vartanian SM| 2022-07-16 | PubMed
Limb-based patency as a measure of effective revascularization for chronic limb-threatening ischemia.
El Khoury R, Wu B, Kupiec-Weglinski SA, Liu IH, Edwards CT, Lancaster EM, Hiramoto JS, Vartanian SM, Schneider PA, Conte MS| 2022-06-10 | PubMed
Applicability of the Vascular Quality Initiative mortality prediction model for infrainguinal revascularization in a tertiary limb preservation center population.
El Khoury R, Wu B, Kupiec-Weglinski SA, Dang LE, Edwards CT, Lancaster EM, Hiramoto JS, Vartanian SM, Schneider PA, Simons JP, Conte MS| 2022-03-18 | PubMed
Toward endovascular treatment of type A aortic dissection with smaller landing zones and more patient eligibility.
Wisneski AD, Kumar V, Vartanian SM, Oskowitz AZ| 2021-09-06 | PubMed
Pedal arterial calcification score is associated with the risk of major amputation in chronic limb-threatening ischemia.
Liu IH, Wu B, Krepkiy V, Ferraresi R, Reyzelman AM, Hiramoto JS, Schneider PA, Conte MS, Vartanian SM| 2021-09-03 | PubMed
Transvenous Type 2 Endoleak Embolization Using Intravascular Ultrasound Guidance via a Left-Sided Inferior Vena Cava.
Hicks RM, Vartanian SM, Lehrman ED| 2021-05-24 | PubMed
Contemporary Experience with Paravisceral Aortic Aneurysm (PVAAA) Repair in a Tertiary Center.
Zarkowsky DS, Inman JT, Sorrentino TA, Hiramoto JS, Vartanian SM, Eichler CM, Reilly LM, Gasper WJ, Conte MS| 2021-04-02 | PubMed
Comparison of Ellipsys Percutaneous and Proximal Forearm Gracz-Type Surgical Arteriovenous Fistulas.
Shahverdyan R, Beathard G, Mushtaq N, Litchfield TF, Vartanian S, Konner K, Jennings WC| 2021-03-01 | PubMed
The Global Limb Anatomic Staging System is associated with outcomes of infrainguinal revascularization in chronic limb threatening ischemia.
El Khoury R, Wu B, Edwards CT, Lancaster EM, Hiramoto JS, Vartanian SM, Schneider PA, Conte MS| 2021-02-04 | PubMed
Impact of the coronavirus disease 2019 pandemic on an academic vascular practice and a multidisciplinary limb preservation program.
Lancaster EM, Wu B, Iannuzzi J, Oskowitz A, Gasper W, Vartanian S, Wick E, Hiramoto J, Eichler C, Lobo E, Reyzelman A, Reilly L, Sosa JA, Conte MS| 2020-09-12 | PubMed
Natural history of acute pediatric iliofemoral artery thrombosis treated with anticoagulation.
Ramirez JL, Kuhrau CR, Wu B, Zarkowsky DS, Conte MS, Oskowitz AZ, Nijagal A, Vartanian SM| 2020-04-08 | PubMed
Antegrade common femoral artery closure device use is associated with decreased complications.
Ramirez JL, Zarkowsky DS, Sorrentino TA, Hicks CW, Vartanian SM, Gasper WJ, Conte MS, Iannuzzi JC| 2020-03-09 | PubMed
Functional outcomes of arteriovenous fistulas recruited with regional anesthesia.
Zarkowsky DS, Wu B, Gray AT, Oskowitz AZ, Vartanian SM| 2020-02-01 | PubMed
Contributions of HIV, hepatitis C virus, and traditional vascular risk factors to peripheral artery disease in women.
Cedarbaum E, Ma Y, Scherzer R, Price JC, Adimora AA, Bamman M, Cohen M, Fischl MA, Matsushita K, Ofotokun I, Plankey M, Seaberg EC, Yin MT, Grunfeld C, Vartanian S, Sharma A, Tien PC| 2019-11-01 | PubMed
Congenital superior mesenteric artery aneurysm in a 6-week-old infant presenting with upper gastrointestinal bleeding.
Subbaraj L, Beleniski F, Courtier J, Vartanian S, Nijagal A| 2019-08-07 | PubMed
In vitro and in vivo hemocompatibility assessment of ultrathin sulfobetaine polymer coatings for silicon-based implants.
Iqbal Z, Kim S, Moyer J, Moses W, Abada E, Wright N, Kim EJ, Park J, Fissell WH, Vartanian S, Roy S| 2019-03-12 | PubMed
The impact of prior aortic surgery on outcomes after multibranched endovascular aortic aneurysm repair.
Kaushik S, Gasper WJ, Ramanan B, Vartanian SM, Reilly LM, Chuter TAM, Hiramoto JS| 2018-03-06 | PubMed
A mixed-methods investigation of incident Hemodialysis access in a safety-net population.
Rich NC, Vartanian SM, Sharief S, Freitas DJ, Tuot DS| 2017-09-02 | PubMed
Determinants of midterm functional outcomes, wound healing, and resources used in a hospital-based limb preservation program.
Ramanan B, Ahmed A, Wu B, Causey MW, Gasper WJ, Vartanian SM, Reyzelman AM, Hiramoto JS, Conte MS| 2017-08-18 | PubMed
Correction: An intravascular bioartificial pancreas device (iBAP) with silicon nanopore membranes (SNM) for islet encapsulation under convective mass transport.
Song S, Blaha C, Moses W, Park J, Wright N, Groszek J, Fissell W, Vartanian S, Posselt AM, Roy S| 2017-06-27 | PubMed
An intravascular bioartificial pancreas device (iBAP) with silicon nanopore membranes (SNM) for islet encapsulation under convective mass transport.
Song S, Blaha C, Moses W, Park J, Wright N, Groszek J, Fissell W, Vartanian S, Posselt AM, Roy S| 2017-05-16 | PubMed
Lower extremity weakness is associated with elevated blood and cerebrospinal fluid glucose levels following multibranched endovascular aortic aneurysm repair.
Hiramoto JS, Fernandez C, Gasper W, Vartanian S, Reilly L, Chuter T| 2016-11-19 | PubMed
Society for Vascular Surgery limb stage and patient risk correlate with outcomes in an amputation prevention program.
Causey MW, Ahmed A, Wu B, Gasper WJ, Reyzelman A, Vartanian SM, Hiramoto JS, Conte MS| 2016-03-29 | PubMed
Low-profile versus standard-profile multibranched thoracoabdominal aortic stent grafts.
Ramanan B, Fernandez CC, Sobel JD, Gasper WJ, Vartanian SM, Reilly LM, Chuter TA, Hiramoto JS| 2016-03-22 | PubMed
Standard off-the-shelf versus custom-made multibranched thoracoabdominal aortic stent grafts.
Fernandez CC, Sobel JD, Gasper WJ, Vartanian SM, Reilly LM, Chuter TA, Hiramoto JS| 2016-01-24 | PubMed
Risk Factors for 30-Day Hospital Readmission in Patients Undergoing Treatment for Peripheral Artery Disease.
Han SM, Wu B, Eichler CM, Reilly LM, Vartanian SM, Conte MS, Hiramoto J| 2015-07-05 | PubMed
Surgical intervention for peripheral arterial disease.
Vartanian SM, Conte MS| 2015-04-24 | PubMed
Outcomes of neuroischemic wounds treated by a multidisciplinary amputation prevention service.
Vartanian SM, Robinson KD, Ofili K, Eichler CM, Hiramoto JS, Reyzelman AM, Conte MS| 2015-01-14 | PubMed
Lower extremity weakness after endovascular aneurysm repair with multibranched thoracoabdominal stent grafts.
Sobel JD, Vartanian SM, Gasper WJ, Hiramoto JS, Chuter TA, Reilly LM| 2014-11-25 | PubMed
Clinical consequence of bare metal stent and stent graft failure in femoropopliteal occlusive disease.
Vartanian SM, Johnston PC, Walker JP, Runge SJ, Eichler CM, Reilly LM, Hiramoto JS, Conte MS| 2013-07-30 | PubMed
Risk factors for clinical failure after stent graft treatment for femoropopliteal occlusive disease.
Johnston PC, Vartanian SM, Runge SJ, Hiramoto JS, Eichler CM, Owens CD, Schneider DB, Conte MS| 2012-05-25 | PubMed
Endothelial Notch4 signaling induces hallmarks of brain arteriovenous malformations in mice.
Murphy PA, Lam MT, Wu X, Kim TN, Vartanian SM, Bollen AW, Carlson TR, Wang RA| 2008-07-30 | PubMed
Therapeutic angiogenesis.
Vartanian SM, Sarkar R| 2007-06-01 | PubMed
Oklahoma prosthesis: resection of tumor of clavicle and chest wall reconstructed with a custom composite graft.
Vartanian SM, Colaco S, Orloff LE, Theodore PR| 2006-07-01 | PubMed
Ischemic colitis: spectrum of disease and outcome.
Scharff JR, Longo WE, Vartanian SM, Jacobs DL, Bahadursingh AN, Kaminski DL| 2003-10-01 | PubMed
Laparoscopic hernioplasty: significant complications.
Felix EL, Harbertson N, Vartanian S| 1999-04-01 | PubMed

Resources