Biography
Kukreja is the associate director of UCSF's lung transplant research division of cardiothoracic surgery.
Kukreja earned a medical degree at the David Geffen School of Medicine at UCLA. She completed residencies in general surgery at Brigham and Women's Hospital in Boston and in cardiothoracic surgery at UCSF. She completed fellowships in general surgery and thoracic surgery at Brigham and Women's Hospital, and also completed extensive training in designing clinical trials, studies that evaluate potential treatments' safety and efficacy. She has a master's degree in public health from the Harvard T.H. Chan School of Public Health.
Kukreja has received many professional honors, including the Pharmacia/Upjohn Trauma Research Competition Award, John A. Mannick Research Award and an excellence in teaching award from Harvard Medical School.
Education
Institution | Degree | Dept or School | End Date |
---|---|---|---|
University of California | Diversity, Equity, and Inclusion Champion Training | 2018 | |
University of California Los Angeles | M.D. | School of Medicine | 1994 |
University of California, San Francisco | Postdoctoral Studies | Graduate Division |
Board Certifications
American Board of Surgery, General Surgery
American Board of Thoracic Surgery, Thoracic and Cardiac Surgery
Clinical Expertise
Bronchioloalveolar Carcinoma (BAC)
Carcinoid Tumors
Chest Wall Tumors
Esophageal Cancer
Esophagectomy
Lung Metastases
Lung Transplantation
Lung Volume Reduction Surgery
Malignant Mesothelioma
Mediastinal Masses
Minimally Invasive Thoracic Surgery
Non-Small Cell Lung Cancer
Sarcomas
Small-Cell Lung Cancer
Tracheal Tumors
Video-Assisted Thoracoscopic Surgery (VATS)
Clinical Trials
- Related Conditions: Lung Transplant| Start Date: | End Date:
- 10°C Vs 4°C Lung Preservation RCT (NCT05898776)Related Conditions: Lung Transplant, Transplants, Organ Preservation| Start Date: | End Date:
- OCS Lung System EXPAND II Trial (NCT03343535)Related Conditions: Lung Transplant| Start Date: | End Date:
- International EXPAND Lung Pivotal Trial (NCT01963780)Related Conditions: Lung Transplant, Transplants| Start Date: | End Date:
Program Affiliations
Thoracic Oncology Program, UCSF Helen Diller Family Comprehensive Cancer Center
Lung Transplantation, UCSF Heart and Lung Transplantation Program
San Francisco Veterans Administration Hospital
Contra Costa Regional Medical Center
In the News
Research Interests
- Novel therapies for lung cancer
- Clinical trials for new surgical modalities
Publications
- Improvements in Patient-Reported Functioning after Lung Transplant is Associated with Improved Quality of Life and Survival.| | PubMed
- CD94+ natural killer cells potentiate pulmonary ischaemia-reperfusion injury.| | PubMed
- Disturbed sleep after lung transplantation is associated with worse patient-reported outcomes and chronic lung allograft dysfunction.| | PubMed
- MICB Genomic Variant Is Associated with NKG2D-mediated Acute Lung Injury and Death.| | PubMed
- CCR5 drives NK cell-associated airway damage in pulmonary ischemia-reperfusion injury.| | PubMed
- Outcomes of Lung Transplantation for Idiopathic Pulmonary Fibrosis: Glass Half Full or Still Half Empty?| | PubMed
- Short airway telomeres are associated with primary graft dysfunction and chronic lung allograft dysfunction.| | PubMed
- Decreased Lymphocytic Bronchitis Severity in the Era of Azithromycin Prophylaxis.| | PubMed
- Prone Positioning After Lung Transplantation Remains Prone to Debate.| | PubMed
- Management of primary graft dysfunction after lung transplantation with extracorporeal life support: an evidence-based review.| | PubMed
- Biofire pneumonia panel in lung donors: faster detection but limited pathogens.| | PubMed
- The Association Between Frailty and Chronic Lung Allograft Dysfunction After Lung Transplantation.| | PubMed
- Regadenoson Is All the RAGE: Targeting the Inflammatory Cascade in Primary Graft Dysfunction.| | PubMed
- Perioperative Fluid Management.| | PubMed
- Lung preservation: from perfusion to temperature.| | PubMed
- Development of the Lung Transplant Frailty Scale (LT-FS).| | PubMed
- Lungs Preserved on Ice or in a Refrigerator? Prolonged Static Lung Storage at 10 °C.| | PubMed
- Subphenotypes of frailty in lung transplant candidates.| | PubMed
- Design and implementation of a digital health home spirometry intervention for remote monitoring of lung transplant function.| | PubMed
- The Lung Allocation Score Remains Inequitable for Patients with Pulmonary Arterial Hypertension, Even after the 2015 Revision.| | PubMed
- Addressing sex-based disparities in solid organ transplantation in the United States - a conference report.| | PubMed
- CD16+ natural killer cells in bronchoalveolar lavage are associated with antibody-mediated rejection and chronic lung allograft dysfunction.| | PubMed
- Frailty and genetic risk predict fracture after lung transplantation.| | PubMed
- Echocardiographic estimation of pulmonary vascular resistance in advanced lung disease.| | PubMed
- NKG2D receptor activation drives primary graft dysfunction severity and poor lung transplantation outcomes.| | PubMed
- The American Association for Thoracic Surgery (AATS) 2022 Expert Consensus Document: The use of mechanical circulatory support in lung transplantation.| | PubMed
- Intercostal Nerve Cryoanalgesia Versus Thoracic Epidural Analgesia in Lung Transplantation: A Retrospective Single-Center Study.| | PubMed
- Contemporary trends in PGD incidence, outcomes, and therapies.| | PubMed
- ISHLT consensus statement: Perioperative management of patients with pulmonary hypertension and right heart failure undergoing surgery.| | PubMed
- Chronic Lung Allograft Dysfunction.| | PubMed
- Early Postoperative Management of Lung Transplant Recipients.| | PubMed
- Depressive symptoms in lung transplant recipients: trajectory and association with mortality and allograft dysfunction.| | PubMed
- Inflammation on bronchoalveolar lavage cytology is associated with decreased chronic lung allograft dysfunction-free survival.| | PubMed
- Lung transplant recipients with idiopathic pulmonary fibrosis have impaired alloreactive immune responses.| | PubMed
- Lung Allograft Epithelium DNA Methylation Age Is Associated With Graft Chronologic Age and Primary Graft Dysfunction.| | PubMed
- Construct and Predictive Validity of Sarcopenia in Lung Transplant Candidates.| | PubMed
- Lung Transplantation for Patients With COVID-19.| | PubMed
- ISHLT consensus document on lung transplantation in patients with connective tissue disease: Part III: Pharmacology, medical and surgical management of post-transplant extrapulmonary conditions statements.| | PubMed
- Molecular markers of telomere dysfunction and senescence are common findings in the usual interstitial pneumonia pattern of lung fibrosis.| | PubMed
- The association of post-operative delirium with patient-reported outcomes and mortality after lung transplantation.| | PubMed
- Lung transplantation from swimming pool drowning victims: A case series.| | PubMed
- Rapid molecular detection of airway pathogens in lung transplant recipients.| | PubMed
- Mobile health technology to improve emergent frailty after lung transplantation.| | PubMed
- Natural killer cells activated through NKG2D mediate lung ischemia-reperfusion injury.| | PubMed
- Complement activation on endothelium initiates antibody-mediated acute lung injury.| | PubMed
- Airway Epithelial Telomere Dysfunction Drives Remodeling Similar to Chronic Lung Allograft Dysfunction.| | PubMed
- An Analysis of Successful Features of Anesthesiology Journal Clubs.| | PubMed
- Primary graft dysfunction attenuates improvements in health-related quality of life after lung transplantation, but not disability or depression.| | PubMed
- Cystic Fibrosis Lung Transplant Recipients Have Suppressed Airway Interferon Responses during Pseudomonas Infection.| | PubMed
- Clinical outcomes and serologic response in solid organ transplant recipients with COVID-19: A case series from the United States.| | PubMed
- Lung transplant programs in developing countries: challenges, solutions, and outcomes.| | PubMed
- Redefining marginality: donor lung criteria.| | PubMed
- Skeletal muscle adiposity and outcomes in candidates for lung transplantation: a lung transplant body composition cohort study.| | PubMed
- Risk Factors and Outcomes of Extracorporeal Membrane Oxygenation as a Bridge to Lung Transplantation.| | PubMed
- Frailty after lung transplantation is associated with impaired health-related quality of life and mortality.| | PubMed
- Donor heart and lung procurement: A consensus statement.| | PubMed
- Improvements in frailty contribute to substantial improvements in quality of life after lung transplantation in patients with cystic fibrosis.| | PubMed
- Improved survival after lung transplantation for adults requiring preoperative invasive mechanical ventilation: A national cohort study.| | PubMed
- Mitochondrial DNA Stimulates TLR9-Dependent Neutrophil Extracellular Trap Formation in Primary Graft Dysfunction.| | PubMed
- Tacrolimus trough monitoring guided by mass spectrometry without accounting for assay differences is associated with acute kidney injury in lung transplant recipients.| | PubMed
- Dectin-1 genetic deficiency predicts chronic lung allograft dysfunction and death.| | PubMed
- Adipose tissue quantification and primary graft dysfunction after lung transplantation: The Lung Transplant Body Composition study.| | PubMed
- Portable normothermic ex-vivo lung perfusion, ventilation, and functional assessment with the Organ Care System on donor lung use for transplantation from extended-criteria donors (EXPAND): a single-arm, pivotal trial.| | PubMed
- A nonlinear relationship between visceral adipose tissue and frailty in adult lung transplant candidates.| | PubMed
- Management and clinical outcomes after lung transplantation in patients with pre-transplant Mycobacterium abscessus infection: A single center experience.| | PubMed
- Development and Preliminary Validation of the Lung Transplant Quality of Life (LT-QOL) Survey.| | PubMed
- Time-efficient, goal-directed, and evidence-based teaching in the ICU.| | PubMed
- Gene signatures common to allograft rejection are associated with lymphocytic bronchitis.| | PubMed
- Frailty trajectories in adult lung transplantation: A cohort study.| | PubMed
- NKG2C Natural Killer Cells in Bronchoalveolar Lavage Are Associated With Cytomegalovirus Viremia and Poor Outcomes in Lung Allograft Recipients.| | PubMed
- Histopathological and molecular analysis of idiopathic pulmonary fibrosis lungs from patients treated with pirfenidone or nintedanib.| | PubMed
- Pirfenidone-Induced Sarcoid-Like Reaction: A Novel Complication.| | PubMed
- Genotypes associated with tacrolimus pharmacokinetics impact clinical outcomes in lung transplant recipients.| | PubMed
- Surgical Management of Pulmonary Mucormycosis in Third-Trimester Pregnancy.| | PubMed
- A mobile health technology enabled home-based intervention to treat frailty in adult lung transplant candidates: A pilot study.| | PubMed
- Suppressed calcineurin-dependent gene expression identifies lung allograft recipients at increased risk of infection.| | PubMed
- Frailty phenotypes and mortality after lung transplantation: A prospective cohort study.| | PubMed
- Normothermic ex-vivo preservation with the portable Organ Care System Lung device for bilateral lung transplantation (INSPIRE): a randomised, open-label, non-inferiority, phase 3 study.| | PubMed
- Elevated donor plasminogen activator inhibitor-1 levels and the risk of primary graft dysfunction.| | PubMed
- Improvement in patient-reported outcomes after lung transplantation is not impacted by the use of extracorporeal membrane oxygenation as a bridge to transplantation.| | PubMed
- Refining Low Physical Activity Measurement Improves Frailty Assessment in Advanced Lung Disease and Survivors of Critical Illness.| | PubMed
- Report of the ISHLT Working Group on primary lung graft dysfunction Part IV: Prevention and treatment: A 2016 Consensus Group statement of the International Society for Heart and Lung Transplantation.| | PubMed
- Discharge against Medical Advice in Surgical Patients with Posttraumatic Stress Disorder: A Case Report Series Illustrating Unique Challenges.| | PubMed
- HLA Mismatching Favoring Host-Versus-Graft NK Cell Activity Via KIR3DL1 Is Associated With Improved Outcomes Following Lung Transplantation.| | PubMed
- Short lung transplant donor telomere length is associated with decreased CLAD-free survival.| | PubMed
- Adverse outcomes associated with pulmonary hypertension in chronic obstructive pulmonary disease after bilateral lung transplantation.| | PubMed
- Protein biomarkers associated with primary graft dysfunction following lung transplantation.| | PubMed
- Effect of Lung Transplantation on Health-Related Quality of Life in the Era of the Lung Allocation Score: A U.S. Prospective Cohort Study.| | PubMed
- Donor-Reactive Regulatory T Cell Frequency Increases During Acute Cellular Rejection of Lung Allografts.| | PubMed
- Serotonin Syndrome Following an Uncomplicated Orthopedic Surgery in a Patient With Post-Traumatic Stress Disorder.| | PubMed
- miR-34 miRNAs Regulate Cellular Senescence in Type II Alveolar Epithelial Cells of Patients with Idiopathic Pulmonary Fibrosis.| | PubMed
- Frailty Phenotypes, Disability, and Outcomes in Adult Candidates for Lung Transplantation.| | PubMed
- Prolonged Barium-Impaction Ileus in Two Lung Transplant Recipients With Systemic Sclerosis: Case Report.| | PubMed
- Voriconazole Exposure and Risk of Cutaneous Squamous Cell Carcinoma, Aspergillus Colonization, Invasive Aspergillosis and Death in Lung Transplant Recipients.| | PubMed
- Lung transplantation for hypersensitivity pneumonitis.| | PubMed
- Clinical outcomes of lung transplant recipients with telomerase mutations.| | PubMed
- Body composition and mortality after adult lung transplantation in the United States.| | PubMed
- Belatacept for Maintenance Immunosuppression in Lung Transplantation.| | PubMed
- Heterogeneous gene expression signatures correspond to distinct lung pathologies and biomarkers of disease severity in idiopathic pulmonary fibrosis.| | PubMed
- Prognostic molecular assay might improve identification of patients at risk for recurrence in early-stage non-small-cell lung cancer.| | PubMed
- Divergent management strategies for typical versus atypical carcinoid tumors of the thoracic cavity.| | PubMed
- The feasibility of lung transplantation in HIV-seropositive patients.| | PubMed
- Accumulation of BDCA1⁺ dendritic cells in interstitial fibrotic lung diseases and Th2-high asthma.| | PubMed
- Pulmonary interstitial emphysema in adults: a clinicopathologic study of 53 lung explants.| | PubMed
- Bronchoalveolar lavage cell immunophenotyping facilitates diagnosis of lung allograft rejection.| | PubMed
- Development and validation of a lung transplant-specific disability questionnaire.| | PubMed
- Extracorporeal life support for acute respiratory distress syndromes.| | PubMed
- Outcomes in systemic sclerosis-related lung disease after lung transplantation.| | PubMed
- Preoperative CT-Guided percutaneous wire localization of ground glass pulmonary nodules with a modified Kopans wire.| | PubMed
- A thematic analysis of quality of life in lung transplant: the existing evidence and implications for future directions.| | PubMed
- Scedosporium prolificans pericarditis and mycotic aortic aneurysm in a lung transplant recipient receiving voriconazole prophylaxis.| | PubMed
- Extracorporeal membrane oxygenation as a bridge to pulmonary transplantation.| | PubMed
- Cleaved cytokeratin-18 is a mechanistically informative biomarker in idiopathic pulmonary fibrosis.| | PubMed
- Rapidly progressive pulmonary venoocclusive disease in young women taking oral contraceptives.| | PubMed
- Outcomes for lung transplantation for lung cancer in the United Network for Organ Sharing Registry.| | PubMed
- The 4G/4G genotype of the PAI-1 (serpine-1) 4G/5G polymorphism is associated with decreased lung allograft utilization.| | PubMed
- Survival following lung transplantation for silicosis and other occupational lung diseases.| | PubMed
- Ambulatory venovenous extracorporeal respiratory support as a bridge for cystic fibrosis patients to emergent lung transplantation.| | PubMed
- Posterior glenohumeral joint dislocation: a rare complication of central venous cannulation in a patient undergoing coronary artery surgery.| | PubMed
- Sudden onset of atrial flutter during continuous venovenous hemodialysis.| | PubMed
- Epidemiology of non-small cell lung cancer in Asian Americans: incidence patterns among six subgroups by nativity.| | PubMed
- Malignant pleural mesothelioma: overview of the North American and European experience.| | PubMed
- Occult breast carcinoma in reduction mammaplasty specimens: 14-year experience.| | PubMed
- Section IV: selective use of neoadjuvant therapy.| | PubMed